Hi! There are studies showing similar results whether fenbendazole is taken daily or on an alternating schedule (e.g., 4–5 days on, 2–3 days off). Regular lab work is very important during this kind of protocol to monitor liver and kidney function. Dosage should always be tailored based on body weight and overall health status. There’s no one-size-fits-all answer—it really depends on the individual case. Consistency, monitoring, and adjusting as needed are key.
That said, In most monitored cases, fenbendazole appears to be generally well-tolerated and safe when used at appropriate dosage levels based on body weight.
your wonderful for doing this. we have heard joe tippens say that he takes fenben every day, and that its a sort of myth to take for only 4 days a week. is this true? can fenben be taken every day? this would be so helpful in the fight for pets. any thoughts?
Thank you for sharing. I just found out last week that my yellow lab has the same type of lymphoma. Hi just happened to run across your substack and I'm so thankful
Hi we started slower as we were getting advice from medical exports and putting together the idea and ensuring our dog could tolerate the protocol. I think with 3 days off and regular lab testing you should be fine. The lab testing will tell you if there is any issues with the liver or kidneys.
Hi Jon. I have a 10 year old golden who was just diagnosed with lymphoma and started chemotherapy Monday. The only complication at the moment is his liver values are high which they said could be from the 2 eeeks of prednisone he was on prior to starting treatment. And the CCNU protocol can be hard on the liver so they gave him a medication to help detox the liver.
I was to start him on the Ruby Protocol in conjunction with the chemotherapy.
Based on what I’ve read here and elsewhere it appears that I should wait til his liver values return to normal ??
That is very promising. Ruby did chemo for over 6 months until it became resistant to all conventional treatments. I wish we had started the protocol earlier, it absolutely helped her, we were just too late to figuring it all out. As you probably know, lymphoma is aggressive and so early intervention is critical. I wish you all the best in your pups healing journey and feel free to reach out to me or Jon if you need anything.
With a heavy heart I must tell you that we had to let go of our lab Gunner yesterday. He just quit eating and there was really nothing that we could do to make him eat. Can't survive ideas and eating.
I am so sorry to read this, my heart goes out to you. Healing will take it's time for you and those that loved Gunner. My heart is truly with you right now. I know there are no words that can ease this kind of pain, and I can only imagine how much you're hurting. Grief takes time, and it’s different for everyone—please know that whatever you’re feeling is okay. I am so very sorry.
Is there a reputable place to purchase these supplements? I found out yesterday that my sweet lab got diagnosed with splenic sarcoma and I am devastated. They said I have about 2 months left with him
Her appetite remained strong as long as we followed a cycle of four days on and three days off. We had to rotate tripe and dehydrated meat to keep things varied. She wasn’t fond of taking multiple pills, so we switched to a syringe solution or mixed the medication into several small food portions throughout the day. The syringe method was easier, except for turmeric, which worked better in pill form. Fortunately, the peptides didn’t make her sick—she just disliked taking so many pills, though she didn’t mind at first.
We have an American Bully named Artimus or Artie as we call her, she is 5 and diagnosed with Indulent Lymphoma, I am curious how the protocol effects her appetite, Does the Fenbendazole daily for 4 days kill her appetite, is she sick as she would be with Kemo ? We have been told there is no need for treatment at this point, however if there is a chance of reducing the growth of her lymph nodes and giving her renewed energy.... also are there any vets or oncology vets who would support you or us in administering the treatment. Thank you for posting this site, I saw the combo on Joe Rogan and started looking for Pet health. Do you know anything about stem cell treatment, does it help with Cancer, and is there anything we should absolutely avoid.
Should I wait til liver values are back to normal?
Also I’ve read elsewhere with humans they recommend suspending the febenadazol for a couple days before and after chemo so the chemo is more effective. Can you please advise? The oncologist we are working with really does not know anything about these alternatives therapies and cannot advise
I started your protocol two weeks ago. The first week I only fendazole and she had no issues. This week I added ivermectin and a couple of days in she started diarrhea. Is this to be expected?
My dog was recently diagnosed with PV (Polycythemia Vera) and they want to do a huge and expensive workup. I can't afford the $1200 on the work up alone just to figure it if it's primary or secondary. Then the cancer treatment would be very cost prohibitive. Do you have anyone else who has a protocol for PV? Any resources are appreciated
Hi Jon, I'm new here and admittedly not very tech savvy. Are you able to share a reliable source for Ivermectin and Fenbendazole please? Also, do you have any experience with methylene blue? Any help would be much appreciated 🙏
Methylene blue wasn’t part of the original protocol. In humans, it’s being studied for potential anti-cancer effects through mechanisms like mitochondrial support, reducing oxidative stress, and improving cellular respiration—especially in combination with metabolic therapies.
In dogs, the research is limited but emerging. Some integrative vets and practitioners are starting to use it for chronic illness, cognitive decline, and even cancer, though it’s still very much off-label and should be used with caution.
Here’s a good overview specifically on canine use of methylene blue:
Hi Jon, I came across your post while searching for alternatives for our beloved pup, Hank. After reading through, I promptly created a substack account in hopes of reaching you. So, please forgive me as I’m new to navigating this forum.
On March 7th, our sweet 8 year-old 76 pound lapdog decided not to eat his whole portion of food. He never turns down a meal and believe it or not— he has never been sick before. Even more startling, he did the same thing Saturday and Sunday in refusing to eat his full meal despite my pleas. We promptly had him in the vet’s office that Monday, where we were horrified to learn that we may be dealing with lymphoma based on his clinical symptoms. Further testing has now confirmed our fears as of this Monday, March 17th.
My question is how did you purchase the ivermectin and fenbendazole for your sweet Ruby? While I will certainly ask our vet, I’m not sure he would outright prescribe that for Hank. Is there a way to purchase from a website or virtual vet?
As an FYI: I tried messaging you directly, but for some reason it wouldn’t go through. (It could be my mistake as I’m so new to this site.) Praying you see this soon as I’m desperate to find support for our baby. Thank you so much.
EDITING TO NOTE— my apologies, after investigating further, I now understand you were able to order on the websites you sourced above without an actual vet prescription.
Hey Jon, thank you for all the information. I have an English bulldog who has lymphoma and this has cause her right hind leg to swell. I am looking to get her started on this protocol as she is old and chemo is not an option. She is 43lbs.
I am thinking of doing Ivermectin, fenben, and vitamin E. What do you think?
My baby. I miss her so much. I hope this helps as many dogs as it possibly can.
Hi! There are studies showing similar results whether fenbendazole is taken daily or on an alternating schedule (e.g., 4–5 days on, 2–3 days off). Regular lab work is very important during this kind of protocol to monitor liver and kidney function. Dosage should always be tailored based on body weight and overall health status. There’s no one-size-fits-all answer—it really depends on the individual case. Consistency, monitoring, and adjusting as needed are key.
That said, In most monitored cases, fenbendazole appears to be generally well-tolerated and safe when used at appropriate dosage levels based on body weight.
your wonderful for doing this. we have heard joe tippens say that he takes fenben every day, and that its a sort of myth to take for only 4 days a week. is this true? can fenben be taken every day? this would be so helpful in the fight for pets. any thoughts?
Thank you for sharing. I just found out last week that my yellow lab has the same type of lymphoma. Hi just happened to run across your substack and I'm so thankful
You are welcome. I will be updating this with more in depth information on each topic. Feel free to reach out if needed.
Hi we started slower as we were getting advice from medical exports and putting together the idea and ensuring our dog could tolerate the protocol. I think with 3 days off and regular lab testing you should be fine. The lab testing will tell you if there is any issues with the liver or kidneys.
Hi Jon. I have a 10 year old golden who was just diagnosed with lymphoma and started chemotherapy Monday. The only complication at the moment is his liver values are high which they said could be from the 2 eeeks of prednisone he was on prior to starting treatment. And the CCNU protocol can be hard on the liver so they gave him a medication to help detox the liver.
I was to start him on the Ruby Protocol in conjunction with the chemotherapy.
Based on what I’ve read here and elsewhere it appears that I should wait til his liver values return to normal ??
Another
We tried all conventional methods first but thankfully this protocol extended Ruby’s life another year. I hope it can help you and your beloved lab ❤️
Gunner is 8 1/2 and I hope we can help him. I noticed his lymph nodes were large and the vet said we caught it very early.
That is very promising. Ruby did chemo for over 6 months until it became resistant to all conventional treatments. I wish we had started the protocol earlier, it absolutely helped her, we were just too late to figuring it all out. As you probably know, lymphoma is aggressive and so early intervention is critical. I wish you all the best in your pups healing journey and feel free to reach out to me or Jon if you need anything.
With a heavy heart I must tell you that we had to let go of our lab Gunner yesterday. He just quit eating and there was really nothing that we could do to make him eat. Can't survive ideas and eating.
I’m so sorry for your loss! Labs are the best! I am going through similar with my 8yo lab with a splenic sarcoma that spread
It was so devastating. He was my emotional support dog. It's a big hole that I have right now
I am so sorry to read this, my heart goes out to you. Healing will take it's time for you and those that loved Gunner. My heart is truly with you right now. I know there are no words that can ease this kind of pain, and I can only imagine how much you're hurting. Grief takes time, and it’s different for everyone—please know that whatever you’re feeling is okay. I am so very sorry.
Thank you so much
Hello, did you do the protocol in Ruby for a year without stopping? Only with the 3-day break?
Is there a reputable place to purchase these supplements? I found out yesterday that my sweet lab got diagnosed with splenic sarcoma and I am devastated. They said I have about 2 months left with him
Hi - please DM me - I will share the soruces we found to be good. I cannot say this will work, but it is worth a shot.
Jon I sent you a dm too . Any help thanks !
Me too!!! Same Diag!! Started chemo and we want to include this regimen
How is you baby doing?
Hi Jon! How do I DM you?
I just sent you a direct message - let me know if you got it
How was Rubys appetite does the protocol make them ill
Her appetite remained strong as long as we followed a cycle of four days on and three days off. We had to rotate tripe and dehydrated meat to keep things varied. She wasn’t fond of taking multiple pills, so we switched to a syringe solution or mixed the medication into several small food portions throughout the day. The syringe method was easier, except for turmeric, which worked better in pill form. Fortunately, the peptides didn’t make her sick—she just disliked taking so many pills, though she didn’t mind at first.
We have an American Bully named Artimus or Artie as we call her, she is 5 and diagnosed with Indulent Lymphoma, I am curious how the protocol effects her appetite, Does the Fenbendazole daily for 4 days kill her appetite, is she sick as she would be with Kemo ? We have been told there is no need for treatment at this point, however if there is a chance of reducing the growth of her lymph nodes and giving her renewed energy.... also are there any vets or oncology vets who would support you or us in administering the treatment. Thank you for posting this site, I saw the combo on Joe Rogan and started looking for Pet health. Do you know anything about stem cell treatment, does it help with Cancer, and is there anything we should absolutely avoid.
This is very helpful for the veterinary applications of this amazing medication (s)
Continuing the post
Should I wait til liver values are back to normal?
Also I’ve read elsewhere with humans they recommend suspending the febenadazol for a couple days before and after chemo so the chemo is more effective. Can you please advise? The oncologist we are working with really does not know anything about these alternatives therapies and cannot advise
I started your protocol two weeks ago. The first week I only fendazole and she had no issues. This week I added ivermectin and a couple of days in she started diarrhea. Is this to be expected?
Hi - that can happen - send me a dm - we can discuss - might need to back down a bit
My dog was recently diagnosed with PV (Polycythemia Vera) and they want to do a huge and expensive workup. I can't afford the $1200 on the work up alone just to figure it if it's primary or secondary. Then the cancer treatment would be very cost prohibitive. Do you have anyone else who has a protocol for PV? Any resources are appreciated
Hi Jon, I'm new here and admittedly not very tech savvy. Are you able to share a reliable source for Ivermectin and Fenbendazole please? Also, do you have any experience with methylene blue? Any help would be much appreciated 🙏
No problem happy to help
Methylene blue wasn’t part of the original protocol. In humans, it’s being studied for potential anti-cancer effects through mechanisms like mitochondrial support, reducing oxidative stress, and improving cellular respiration—especially in combination with metabolic therapies.
In dogs, the research is limited but emerging. Some integrative vets and practitioners are starting to use it for chronic illness, cognitive decline, and even cancer, though it’s still very much off-label and should be used with caution.
Here’s a good overview specifically on canine use of methylene blue:
https://thepositive.co/blogs/the-blog/methylene-blue-for-dogs-a-powerful-tool-for-healing-and-recovery
Thank you very much Sir. I sincerely appreciate your help 🙏
Hi Jon, I came across your post while searching for alternatives for our beloved pup, Hank. After reading through, I promptly created a substack account in hopes of reaching you. So, please forgive me as I’m new to navigating this forum.
On March 7th, our sweet 8 year-old 76 pound lapdog decided not to eat his whole portion of food. He never turns down a meal and believe it or not— he has never been sick before. Even more startling, he did the same thing Saturday and Sunday in refusing to eat his full meal despite my pleas. We promptly had him in the vet’s office that Monday, where we were horrified to learn that we may be dealing with lymphoma based on his clinical symptoms. Further testing has now confirmed our fears as of this Monday, March 17th.
My question is how did you purchase the ivermectin and fenbendazole for your sweet Ruby? While I will certainly ask our vet, I’m not sure he would outright prescribe that for Hank. Is there a way to purchase from a website or virtual vet?
As an FYI: I tried messaging you directly, but for some reason it wouldn’t go through. (It could be my mistake as I’m so new to this site.) Praying you see this soon as I’m desperate to find support for our baby. Thank you so much.
EDITING TO NOTE— my apologies, after investigating further, I now understand you were able to order on the websites you sourced above without an actual vet prescription.
Hey no problem I’ll dm you now
Hey Jon, thank you for all the information. I have an English bulldog who has lymphoma and this has cause her right hind leg to swell. I am looking to get her started on this protocol as she is old and chemo is not an option. She is 43lbs.
I am thinking of doing Ivermectin, fenben, and vitamin E. What do you think?
Hi. Please DM me